1117: Khuwyt
One of the Earliest Known Female Musicians
Lived: c. 1960 BCE, Ancient Egypt (Present-day Egypt)
Khuwyt was a singer and musician during the twelfth dynasty of Ancient Egypt. Her name and likeness are recorded in a painting in the tomb of Antefoker, who was a political official at the time.
Khuwyt is therefore considered one of the earliest known female musicians in world history, though of course little else of her life is known today.
Sources:
https://www.brooklynmuseum.org/eascfa/dinner_party/heritage_floor/khuwyt