C:
- Calamity Jane, there's a Reason Her Name was Calamity
- Calpurnia, Wife of Julius Caesar
- Camilla, HRH the Duchess of Cornwall
- Camille Claudel, Sculptor
- Candalyn Kubeck, One of the First Female Commercial Airline Pilots
- Caresse Crosby, Inventor, Publisher, and Businesswoman
- Carlina White, Abducted Child Who Solved Her Own Kidnapping
- Carnie Wilson, Singer and Television Personality
- Carol Greider, Molecular Biologist
- Carol McCain, Director of the White House Visitor's Office
- Caroline Crachami, The Sicilian Fairy
- Caroline Herschel, Astronomer Who Discovered Several Comets
- Caroline Kennedy, Former US Ambassador to Japan
- Caroline Lacroix, Mistress of Leopold II of Belgium
- Carolyn Bessette-Kennedy, Model and Wife of John F Kennedy Jr
- Carrie Ann Inaba, Choreographer and Television Personality
- Carrie Buck, America's Most Famous Victim of the Eugenics Movement
- Carrie Crawford Smith, Ran an Employment Agency to Help Women and Minorities
- Carry Nation, She Vandalized Businesses...Professionally
- Cartimandua, Queen of the Brigantes
- Casey Legler, The First Woman to Be Contracted as a Male Model
- Cathay Williams, The First Woman to Enlist in the US Army
- Catherine of Aragon, Henry VIII's first wife
- Catherine of Valois, Queen Consort of England
- Catherine Cortez Masto, The First Latina State Attorney General and Senator
- Catherine Davidson, Soldier During the War Between the States
- Catherine Farrell Adler, The First Female Marine to Serve in Arlington's Marine Corps Honor Guard
- Catherine "Kitty" Genovese, Murder Victim Whose Death Helped Create the 911 Emergency Alert System
- Catherine Gonsalvus, The Real Beauty
- Catherine the Great, no horses were involved in the writing of this post
- Catherine Howard, Henry VIII's fifth wife
- Catherine HRH The Duchess of Cambridge, Possibly the UK's Future Queen
- Catherine de Medici, Regent, Consort, and Dowager Queen of France (Depending on the Year)
- Catherine O'Leary, Her Life was Ruined by the Rumor That She had Started the Great Chicago Fire
- Catherine Zeta-Jones, Actress
- Cathie Jung, Now That is a Slim Waist
- Catterina Vizzani, a Renaissance Lesbian Crossdresser
- Cecile Dionne, One Fifth of the First Set of Quintuplets Known to Survive Infancy
- Cecilia Payne-Gaposchkin, Astronomer Who Discovered What Makes the Universe
- Chandra Levy, Political Intern Remembered for Her Brutal Murder
- Chandro Tomar, The Oldest Female Sharpshooter in the World at the Time of Her Death
- Ltc. Charity Adams Earley, The First African American Officer in the Women's Army Corps
- Charles Crittenton, Founder of the National Florence Crittenton Mission
- Sergeant Charles Floyd, the only member of the Corps of Discovery to die
- Charles "Chick" Parsons, instrumental in helping General MacArthur return triumphantly to the Philippines during World War II
- Charles Stratton, PT Barnum's greatest asset
- Charlotta Bass, Newspaper Editor and Politician
- Charlotte Badger, Pirate
- Charlotte Brontë, Author
- Charlotte Cooper Sterry, Tennis Player and Olympic Athlete Who Won Five Wimbledon Titles
- Charlotte Parkhurst, Stagecoach Driver in the Old West
- Charlotte Sipes, Who Says Mailing You Can't Mail Your Kid?
- Charlotte von Nassau-Weilburg, Grand Duchess of Luxembourg
- Charlotte Woodward Pierce, Suffragist
- Cher Ami, Carrier Pigeon from World War I
- Cherilyn Sarkisian, aka Cher
- Chien-Shiung Wu, Experimental Physicist
- Ching Shih, from prostitute to one of the most formidable pirates of all time
- Chita Rivera, Broadway Performer
- Chiune Sugihara, he and his wife Yukiko are credited with saving 6,000 Jews during the Shoah
- Christiane Nusslein-Volhard, Nobel Prize Winning Biologist
- Christie Hefner, Former CEO of Playboy Enterprises Inc
- Christina Hoff Sommers, Author and Advocate for Equity Feminism
- Christine Collins, The Real Woman Behind the Film Changeling
- Christine de Pisan, The First Feminist Author
- Christine Maria Margarete Denner, Saved Edith Hahn's Life
- Christine Granville, World War II Spy
- Chyna, Professional WWF Wrestler
- Cindy Crawford, Supermodel
- Cixi, Empress Dowager of China
- Claire Phillips, World War II Spy in Manila
- Claire Schillace Donahoe, All American Girl's Professional Baseball League Player
- Clara Brown, Former Slave who Helped Settle Colorado
- Clara de la Rocha, Soldadera in the Mexican Revolution
- Clara Harris Rathbone, The Other Victim in the Presidential Box
- Clara Petacci, Mussolini's Mistress
- Clara Quintanilla, Art Restorer
- Clare Hollingworth, Pioneering Journalist
- Claressa Shields, Professional Boxer and MMA Fighter
- Clarissa "Clara" Barton, Founder of the American Red Cross
- Claudette Colvin, Refused to Give Up Her Bus Seat Nine Months Before Rosa Parks
- Claudia Octavia, Empress of Rome
- Clementine Churchill, So Much More than Winston's Wife
- Cleopatra I Syra, Queen of Ancient Egypt whose family spread out across the Mediterranean
- Cleopatra I Thea, Queen of the Seleucid Empire
- Cleopatra Selene II, Cleopatra VII's daughter
- Cleopatra VII Philopater, yes, that Cleopatra
- Coco Chanel, Fashion Designer
- Colleen Stan, The Girl in the Box
- Condoleezza Rice, Politician
- Constance Baker Motley, Civil Rights Activist and Federal Judge
- Constance Kent, Murderess
- Constance Markievicz, First Woman Elected to British Parliament (Never Took Her Seat)
- Cora the Witch, Legend Behind the Cora Tree
- Corrie Ten Boom, you probably read her story in school
- Cynisca, Spartan Princess and the First Woman to Win at the Olympic Games
D:
- Daisy Ashford, Wrote Her First Novel Aged Nine
- Daisy Hilton, Conjoined Twin & Vaudeville Performer
- Father Damien, Savior to the Lepers
- Danica Patrick, Retired Indycar Driver
- Darlene Cates, Actress
- Daryl Davis, he's talked to over 200 members of the KKK; and they gave up their robes afterward
- Debbie Allen, Choreographer and So Much More
- Deborah Lipstadt, Shoah Historian
- Deborah Sampson Gannett, Revolutionary War Soldier
- Madame DeCourcelle, The First Female Taxi Driver in Paris
- Delia Haskett Rawson, The First Female Stagecoach Driver in California
- Delphine LaLaurie, not even Kathy Bates could make her sympathetic
- Denise Morrison, former CEO of Campbell Soup Co
- Deshauna Barber, Miss USA 2016 and Army Reserve Logistics Commander
- Desmond Doss, the First Conscientious Objector to be awarded the Medal of Hono
- Diana Spencer, The People's Princess
- Diane de Poitiers, mistress to Henry II of France
- Diane Sawyer, Journalist
- Dina Babbitt, Shoah Survivor and Artist
- Do Won Chang, The American Dream is Alive and Well
- Dolley Madison, Former First Lady during her husband James Madison's Term
- Don Wildman, You know who he is!
- Donaldina Cameron, The Angry Angel of Chinatown
- Donatella Versace, Vice-President of the Versace Group
- Dora DuFran, Successful Madam and Saloon Owner
- Doris Bohrer, Allied Spy and Deputy Head of Counterintelligence at the CIA
- Doris Buck Figgins, Victim of the United States Eugenics Movement
- Doris Zemurray Stone, archaeologist who fought for the rights of the Indigenous of Central America
- Dorothea Dix, Mental Health Advocate who brought the horrific conditions of Insane Asylums to light
- Dorothy Count-Scoggins, Helped End Segregation of Charlotte, North Carolina High Schools
- Dorothy Ferguson Key, All American Girls Professional Baseball League Player
- Dorothy Fosdick, Foreign Policy Expert
- Dorothy Garrod, First Woman to Hold an Oxford and Cambridge Chair; Archaeologist
- Dorothy Hodgkin, Biochemist and Crystallographer
- Dorothy Kamenshek, All-American Girls' Professional Baseball League Player
- Dorothy Morgan, Pioneering Stunt Pilot
- Dorothy Stratton, Commanding Officer of the Coast Guard SPARs (World War II)
- Dorothy Vaughan, Hidden Figure and FORTRAN Programmer
- Douglas Pitt, He's so much more than the Other Pitt
- Draginja Obrenovic, Queen Consort of Serbia
E:
- Earl Olsen, he tried so hard to save Joe Kennedy Jr...so hard
- Edith Brown Haisman, RMS Titanic Survivor
- Edith Clarke, the First Female Electrical Engineer
- Edith Flanigen, Chemist Who Holds Over 100 Patents
- Edith Hahn Beer, The Nazi Officer's Wife
- Edith Piaf, Musician and Actress
- Edith Wilson, Former First Lady of the United States
- Edmonia Lewis, The First Professional African American Sculptor
- Eduard Einstein, the forgotten Einstein son
- Sergeant First-Class Edward Carter Jr, Medal of Honor Recipient who was not awarded right until thirty years after he died
- Edward Younger, the man who selected the first Unknown Soldier
- Ehyophsta, Cheyenne Warrior Woman
- Eileen Nearne, SOE Agent During World War II
- Ekaterina Dolgorukaya, Mistress and Later Wife of Alexander II
- El Chango, Mexican Drug Cartel Monkey
- Elaine Harmon, World War II WASP and Advocate for Her Fellow WASPs
- Eleanor of Aquitaine, one of the most powerful figures from Europe's Middle Ages
- Eleanor Audley, Actress
- Eleanor Roosevelt, the longest serving First Lady of the United States
- Eleanore Dumont, One of the First Professional Blackjack Players in the United States
- Elena Cornaro Piscopia, the First Woman to Ever Earn a Doctoral Degree
- Elie Wiesel, Nobel Prize winning author and teacher
- Elisa Griensen, Fought in the Mexican Revolution
- Elisabeth of Austria, Empress of Austria
- Elisabetta Sirani, One of the Most Famous Painters in Early Modern Bologna
- Eliza Cook, Poet and Political Reformist
- Elizabeth Anderson, the first woman to qualify as a doctor and surgeon with a modern medical degree in Great Britain
- Elizabeth Bacon Custer, Widow of General George Armstrong Custer
- Elizabeth Barrett Browning, Poet
- Elizabeth Blackburn, Nobel Prize Winner and Former President of the Salk Institute
- Elizabeth Blackwell, first woman to receive a modern medical degree from a school in the United States
- Elizabeth Cady Stanton, Suffrage Leader & Social Reformer
- Elizabeth Cowell, First Female TV Announcer
- Elizabeth Fleischman-Aschheim, X-Ray Pioneer
- Elizabeth Freeman, The First Slave to File and Win a Suit for Freedom in Massachusetts
- Elizabeth I, One of England's Greatest Queens
- Elizabeth II, currently England's Longest Reigning Monarch
- Elizabeth Hart Jarvis Colt, The First Lady of Hartford
- Elizabeth Jennings Graham, She Did it 100 Years Before Rosa Parks
- Elizabeth Keckley, Former Slave Turned Seamstress to Mary Todd Lincoln
- Elizabeth Magie, she invented Monopoly (kind of, just read her article)
- Elizabeth Peabody, Educator and Author
- Elizabeth Proctor, Accused of being a Salem Witch
- Elizabeth Rawdon, The First Person to Undertake a Scientific Study of a Bog Body
- Elizabeth Short, The Black Dahlia
- Elizabeth Tabor, The Silver Queen of Colorado
- Elizabeth Taylor, Actress
- Elizabeth Woodville, England's "White Queen"
- Ella Cara Deloria, Yankton Sioux Ethnographer and Anthropologist
- Ella Harper, The Camel Girl
- Ellen Craft, Escaped Slave
- Ellen DeGeneres, Comedian and Actress
- Ellen Rometsch, possible Soviet spy
- Emilie Dionne, One Fifth of the First Set of Quintuplets Known to Survive Infancy
- Emilie Sagee, The Teacher with a Ghostly Follower
- Emilie Schindler, Savior of Jews During the Shoah
- Emily Brontë, Author
- Emily Geiger, Revolutionary War Civilian Volunteer
- Emily Howland, The First Female Director of a US National Bank
- Emily Mather, Murder Victim
- Emily Warren Roebling, Engineer Noted for Her Work in Completing the Brooklyn Bridge
- Emily Wilde, Oscar Wilde's Half-sister
- Emma H Cunningham, she might have committed murder
- Emma Morano, The Oldest Living Person in the World at the Time of Her Death
- Emma Watson, Actress
- Emmy Noether, Mathematician
- Enheduanna, The First Known Author--Ever
- Enriqueta Marti, Serial Killer of Children
- Epicharis, Attempted to Assassinate Nero
- Erika Ervin, Otherwise Known as Amazon Eve
- Erika Szeles, Martyr in the Hungarian Revolution
- Erinna, Ancient Greek Poet
- Erwin Rommel, The Desert Fox
- Erzsebet Bathory, Possibly one of the Most Prolific Serial Killers of All Time
- Estelle Reel, The First Female Superintendent of Indian Schools in US History
- Esther Hobart Morris, The First Female Justice of the Peace in the United States
- Esther Lederberg, Microbiologist
- Etta Place, The Sundance Kid's Wife
- Etta Schureman Jones, Teacher Turned Japanese Prisoner of War
- Ethel Robertson Macia, The First Lady of Tombstone, Arizona
- Second Lieutenant Eugene Bullard, the first man of African descent to become a combat pilot
- Eugene Cernan, the last man to walk on the moon
- Eugene Lazowski, he went above and beyond his calling as a doctor
- Saint Eulalia, Thirteen-Year-Old Christian Martyr
- Eunice Kennedy Shriver, Creator of the Special Olympics
- Eva Braun, if you knew her story, you would gain a whole new perspective
- Eva Gabor, Actress
- Eva Hart, RMS Titanic Survivor
- Eva Mozes Kor, Shoah Survivor and Forgiveness Advocate
- Eva Peron, Former First Lady of Argentina
- Evelyn McHale, Subject of LIFE Magazine's "A Beautiful Suicide" Photograph